API Obeticholic acid CAS 459789-99-2 mo te cholangitis biliary

Whakaahuatanga Poto:

Ko te waikawa Obeticholic e whakamahia takitahi ana, i te maimoatanga whakakotahi ranei mo tetahi mate ate (kolangitis biliary tuatahi-PBC).

Whakapā: Erica Zheng

Email: erica@zhuoerchem.com

Waea: +86 21 2097 0332

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Tukuna he imeera ki a matou

Taipitopito Hua

Tohu Hua

Whakaahuatanga

Ko te waikawa Obeticholic e whakamahia takitahi ana, i te maimoatanga whakakotahi ranei mo tetahi mate ate (kolangitis biliary tuatahi-PBC).

Whakatakotoranga:

Ingoa Hua	Waikawa Obeticholic
Ingoa matū	6-Ethylhenodeoxycholic acid
Ētahi atu Ingoa	3A, 7A -DIHYDROXY-6A -ETHYL-5B-CHOLAN-24-OIC ACID;Obeticholic acid 6-ECDCA;6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6-Ethylchenodeoxycholic acid;6alph;Obeticholic acid 6747 -ECDCA)
Tau CAS	459789-99-2
Tātai rāpoi	C26H44O4
Taumaha Tātai	420.63
Te ahua	Te paura ma
Te whakamatautau	99.0% min
Kiato	1.091 g/cm3
Iwi Whakarewa	108-110 °C
Kohuatanga	562.9±25.0 °C
Mōkī	20kg / putea / pahū, 25kg / putea / pahū, ranei rite hiahia koe
Rokiroki	Whakaorangia te ipu kia kati katia ki tetahi wahi maroke me te makariri.Kaua e pa ki te ra tika.
COA & MSDS	Kei te waatea

Whakamahinga

Ko te waikawa Obeticholic he waikawa dihydroxy-5beta-cholanic he waikawa chenodeoxycholic e mau ana i te taapiri ethyl ki te 6alpha-turanga.He waikawa peera ahua-waihanga e mahi ana hei agonist kaiawhina X farnesoid ka whakamahia mo te maimoatanga o te cholangitis biliary tuatahi.He mahi hei agonist kaiawhina X farnesoid me te kaihoko hepatoprotective.He waikawa dihydroxy-5beta-cholanic, he 3alpha-hydroxy steroid me te 7alpha-hydroxy steroid.I ahu mai i te waikawa chenodeoxycholic.
Ko te waikawa Obeticholic (OCA) he waikawa peera kua whakarerekehia me te agonist kaha o te kaiawhina karihi farnesoid X (FXR) e whakamahia ana ki te rongoa i nga mate ate tae atu ki te cholangitis biliary tuatahi.